1W4Z

Structure of actinorhodin polyketide (actIII) Reductase

Summary for 1W4Z

• Entry DOI: 10.2210/pdb1w4z/pdb
• Descriptor: KETOACYL REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, FORMIC ACID, ... (4 entities in total)
• Functional Keywords: type ii polyketide synthesis, ketoreductase, sdr, acp binding, antibiotic biosynthesis
• Biological source: STREPTOMYCES COELICOLOR
• Total number of polymer chains: 2
• Total formula weight: 60829.76

Authors

Hadfield, A.T.,Limpkin, C.,Teartasin, W.,Simpson, T.J.,Crosby, J.,Crump, M.P. (deposition date: 2004-08-03, release date: 2004-12-10, Last modification date: 2023-12-13)

• Primary citation: Hadfield, A.T.,Limpkin, C.,Teartasin, W.,Simpson, T.J.,Crosby, J.,Crump, M.P.; The Crystal Structure of the Actiii Actinorhodin Polyketide Reductase; Proposed Mechanism for Acp and Polyketide Binding; Structure, 12:1865-, 2004; PubMed: 15458634; DOI: 10.1016/J.STR.2004.08.002

Experimental method

X-RAY DIFFRACTION (2.5 Å)