1W2Y

The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue dUpNHp

1W2Y の概要

• エントリーDOI: 10.2210/pdb1w2y/pdb
• 分子名称: DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDE HYDROLASE, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: dutp pyrophosphatase, dimeric, ligand complex, magnesium ions, pathogen, drug target, hydrolase
• 由来する生物種: CAMPYLOBACTER JEJUNI
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55023.67

構造登録者

Moroz, O.V.,Harkiolaki, M.,Galperin, M.Y.,Vagin, A.A.,Gonzalez-Pacanowska, D.,Wilson, K.S. (登録日: 2004-07-09, 公開日: 2004-09-16, 最終更新日: 2023-12-13)

• 主引用文献: Moroz, O.V.,Harkiolaki, M.,Galperin, M.Y.,Vagin, A.A.,Gonzalez-Pacanowska, D.,Wilson, K.S.; The Crystal Structure of a Complex of Campylobacter Jejuni Dutpase with Substrate Analogue Sheds Light on the Mechanism and Suggests the "Basic Module" for Dimeric D(C/U)Tpases; J.Mol.Biol., 342:1583-, 2004; PubMed: 15364583; DOI: 10.1016/J.JMB.2004.07.050

実験手法

X-RAY DIFFRACTION (1.65 Å)