1VWI

STREPTAVIDIN-CYCLO-[5-S-VALERAMIDE-HPQGPPC]K-NH2, PH 1.5, I222 COMPLEX

Summary for 1VWI

DescriptorSTREPTAVIDIN, PEPTIDE LIGAND CONTAINING HPQ, PENTANOIC ACID, ... (4 entities in total)
Functional Keywordscomplex (biotin-binding protein-peptide), linear thioether-containing peptide engineered, complex (biotin-binding protein-peptide) complex, complex (biotin-binding protein/peptide)
Biological sourceStreptomyces avidinii
Cellular locationSecreted P22629
Total number of polymer chains4
Total molecular weight27860.35
Authors
Katz, B.A.,Cass, R.T. (deposition date: 1997-03-03, release date: 1998-03-18, Last modification date: 2011-07-27)
Primary citation
Katz, B.A.,Cass, R.T.
In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272:13220-13228, 1997
PubMed: 9148939 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.272.20.13220
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.5 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers93.1%4.7%19.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report