1VWG

STREPTAVIDIN COMPLEXED WITH THE HEAD-TO-TAIL DISULFIDE-BONDED PEPTIDE DIMER OF CYCLO-AC-[CHPQGPPC]-NH2, PH 2.5

Summary for 1VWG

DescriptorSTREPTAVIDIN, PEPTIDE LIGAND CONTAINING HPQ (3 entities in total)
Functional Keywordscomplex (biotin-binding protein-peptide), cyclic peptide discovered by phage display, complex (biotin-binding protein-peptide) complex, complex (biotin-binding protein/peptide)
Biological sourceStreptomyces avidinii
Cellular locationSecreted P22629
Total number of polymer chains2
Total molecular weight13828.04
Authors
Katz, B.A.,Cass, R.T. (deposition date: 1997-03-03, release date: 1998-03-18, Last modification date: 2011-11-16)
Primary citation
Katz, B.A.,Cass, R.T.
In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272:13220-13228, 1997
PubMed: 9148939 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.272.20.13220
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.46 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers71.6%9.5%14.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report