1VIK
HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR HOE/BAY 793 ORTHORHOMBIC FORM
1VIK の概要
エントリーDOI | 10.2210/pdb1vik/pdb |
分子名称 | HIV-1 PROTEASE, N-(1-BENZYL-2,3-DIHYDROXY-4-{3-METHYL-2-[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYLAMINO]-BUTYRYLAMINO}-5-PHENYL-PENTYL)-3-METHYL-2-[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYLAMINO]-BUTYRAMIDE (3 entities in total) |
機能のキーワード | aspartyl protease, human immunodeficiency virus, hoe/bay 793: inhibitor design |
由来する生物種 | Human immunodeficiency virus 1 |
細胞内の位置 | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12499 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 22793.05 |
構造登録者 | Lange-Savage, G.,Berchtold, H.,Liesum, A.,Hilgenfeld, R. (登録日: 1997-05-07, 公開日: 1998-12-09, 最終更新日: 2024-02-14) |
主引用文献 | Lange-Savage, G.,Berchtold, H.,Liesum, A.,Budt, K.H.,Peyman, A.,Knolle, J.,Sedlacek, J.,Fabry, M.,Hilgenfeld, R. Structure of HOE/BAY 793 complexed to human immunodeficiency virus (HIV-1) protease in two different crystal forms--structure/function relationship and influence of crystal packing. Eur.J.Biochem., 248:313-322, 1997 Cited by PubMed: 9346283DOI: 10.1111/j.1432-1033.1997.00313.x 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.4 Å) |
構造検証レポート
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