1VCJ

Influenza B virus neuraminidase complexed with 1-(4-Carboxy-2-(3-pentylamino)phenyl)-5-aminomethyl-5-hydroxymethyl-pyrrolidin-2-one

「1UJA」から置き換えられました

1VCJ の概要

• エントリーDOI: 10.2210/pdb1vcj/pdb
• 分子名称: NEURAMINIDASE, 4-[(2R)-2-(AMINOMETHYL)-2-(HYDROXYMETHYL)-5-OXOPYRROLIDIN-1-YL]-3-[(1-ETHYLPROPYL)AMINO]BENZOIC ACID (3 entities in total)
• 機能のキーワード: neuraminidase, benzoic acid inhibitors, small molecule inhibitor, protein-inhibitor complex, hydrolase
• 由来する生物種: Influenza B virus (B/Lee/40)
• 細胞内の位置: Virion membrane (By similarity): P03474
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43680.66

構造登録者

Lommer, B.S.,Ali, S.M.,Bajpai, S.N.,Brouillette, W.J.,Air, G.M.,Luo, M. (登録日: 2004-03-09, 公開日: 2004-03-23, 最終更新日: 2023-12-27)

• 主引用文献: Lommer, B.S.,Ali, S.M.,Bajpai, S.N.,Brouillette, W.J.,Air, G.M.,Luo, M.; A benzoic acid inhibitor induces a novel conformational change in the active site of Influenza B virus neuraminidase.; Acta Crystallogr.,Sect.D, 60:1017-1023, 2004; PubMed: 15159560; DOI: 10.1107/S0907444904006225

実験手法

X-RAY DIFFRACTION (2.4 Å)