1VAR
MITOCHONDRIAL MANGANESE SUPEROXIDE DISMUTASE VARIANT WITH ILE 58 REPLACED BY THR
Summary for 1VAR
Entry DOI | 10.2210/pdb1var/pdb |
Descriptor | MANGANESE SUPEROXIDE DISMUTASE, MANGANESE (III) ION (3 entities in total) |
Functional Keywords | oxidoreductase, manganese, mitochondrion, transit peptide, polymorphism |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P04179 |
Total number of polymer chains | 2 |
Total formula weight | 44551.99 |
Authors | Borgstahl, G.E.O.,Parge, H.E.,Tainer, J.A. (deposition date: 1996-01-04, release date: 1996-06-10, Last modification date: 2024-02-14) |
Primary citation | Borgstahl, G.E.,Parge, H.E.,Hickey, M.J.,Johnson, M.J.,Boissinot, M.,Hallewell, R.A.,Lepock, J.R.,Cabelli, D.E.,Tainer, J.A. Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface. Biochemistry, 35:4287-4297, 1996 Cited by PubMed: 8605177DOI: 10.1021/bi951892w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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