1V39

DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG

1V39 の概要

• エントリーDOI: 10.2210/pdb1v39/pdb
• 分子名称: VP39, S-ADENOSYL-L-HOMOCYSTEINE, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: methyltransferase, rna cap, poly(a) polymerase, vaccinia, mrna processing, transcription
• 由来する生物種: Vaccinia virus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37976.35

構造登録者

Hodel, A.E.,Gershon, P.D.,Quiocho, F.A. (登録日: 1996-12-16, 公開日: 1997-09-17, 最終更新日: 2024-03-06)

主引用文献

Hodel, A.E.,Gershon, P.D.,Shi, X.,Wang, S.M.,Quiocho, F.A.
Specific protein recognition of an mRNA cap through its alkylated base.
Nat.Struct.Biol., 4:350-354, 1997

PubMed Abstract: The specific binding of N7-methylguanine cap analogues to the RNA methyltransferase VP39 was observed through X-ray crystallography, providing a prototypical structure for a complex between a protein and an mRNA 5' cap.

PubMed: 9145102
DOI: 10.1038/nsb0597-350

実験手法

X-RAY DIFFRACTION (1.8 Å)