1V1R
CROSSTALK BETWEEN COFACTOR BINDING AND THE PHOSPHORYLATION LOOP CONFORMATION IN THE BCKD MACHINE
Summary for 1V1R
Entry DOI | 10.2210/pdb1v1r/pdb |
Related | 1DTW 1OLS 1OLU 1OLX 1V11 1V16 1V1M |
Descriptor | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, CHLORIDE ION, ... (8 entities in total) |
Functional Keywords | oxidoreductase, ketoacid dehydrogenase, multi-enzyme complex, acylation, oxidative decarboxylation, maple syrup urine disease, thiamin diphosphate, phosphorylation, flavoprotein |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 83917.09 |
Authors | Li, J.,Wynn, R.M.,Machius, M.,Chuang, J.L.,Karthikeyan, S.,Tomchick, D.R.,Chuang, D.T. (deposition date: 2004-04-22, release date: 2004-06-03, Last modification date: 2023-12-13) |
Primary citation | Li, J.,Wynn, R.M.,Machius, M.,Chuang, J.L.,Karthikeyan, S.,Tomchick, D.R.,Chuang, D.T. Cross-Talk between Thiamin Diphosphate Binding and Phosphorylation Loop Conformation in Human Branched-Chain {Alpha}-Keto Acid Decarboxylase/Dehydrogenase J.Biol.Chem., 279:32968-, 2004 Cited by PubMed: 15166214DOI: 10.1074/JBC.M403611200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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