1V16

CROSSTALK BETWEEN COFACTOR BINDING AND THE PHOSPHORYLATION LOOP CONFORMATION IN THE BCKD MACHINE

Summary for 1V16

Related1DTW 1OLS 1OLU 1OLX 1V11 1V1M 1V1R
Descriptor2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, POTASSIUM ION, ... (9 entities in total)
Functional Keywordsoxidoreductase, ketoacid dehydrogenase, branched-chain, multi-enzyme complex, acylation, oxidative decarboxylation maple syrup urine disease, thiamine diphosphate, phosphorylation, flavoprotein
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total molecular weight84485.99
Authors
Li, J.,Wynn, R.M.,Machius, M.,Chuang, J.L.,Karthikeyan, S.,Tomchick, D.R.,Chuang, D.T. (deposition date: 2004-04-07, release date: 2004-06-03, Last modification date: 2019-05-15)
Primary citation
Li, J.,Wynn, R.M.,Machius, M.,Chuang, J.L.,Karthikeyan, S.,Tomchick, D.R.,Chuang, D.T.
Cross-Talk between Thiamin Diphosphate Binding and Phosphorylation Loop Conformation in Human Branched-Chain {Alpha}-Keto Acid Decarboxylase/Dehydrogenase
J.Biol.Chem., 279:32968-, 2004
PubMed: 15166214 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M403611200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1863 0.6% 2.9% 4.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution