1UZC

THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11

「1H40」から置き換えられました

1UZC の概要

• エントリーDOI: 10.2210/pdb1uzc/pdb
• 分子名称: HYPOTHETICAL PROTEIN FLJ21157 (1 entity in total)
• 機能のキーワード: nuclear protein, transcription, phosphopeptide recognition, rna polymerase ii carboxyl-terminal domain
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 8251.47

構造登録者

Allen, M.D.,Jemth, P.,Friedler, A.,Schon, O.,Bycroft, M. (登録日: 2004-03-09, 公開日: 2004-04-05, 最終更新日: 2024-05-15)

主引用文献

Allen, M.D.,Friedler, A.,Schon, O.,Bycroft, M.
The Structure of an Ff Domain from Human Hypa/Fbp11.
J.Mol.Biol., 323:411-416, 2002

PubMed Abstract: The FF domain is a 60 amino acid residue phosphopeptide-binding module found in a variety of eukaryotic proteins including the transcription elongation factor CA150, the splicing factor Prp40 and p190RHOGAP. We have determined the structure of an FF domain from HYPA/FBP11. The domain is composed of three alpha helices arranged in an orthogonal bundle with a 3(10) helix in the loop between the second and third alpha helices. The structure differs from those of other phosphopeptide-binding domains and represents a novel phosphopeptide-binding fold.

PubMed: 12381297
DOI: 10.1016/S0022-2836(02)00968-3

実験手法

SOLUTION NMR