1UTE

PIG PURPLE ACID PHOSPHATASE COMPLEXED WITH PHOSPHATE

1UTE の概要

• エントリーDOI: 10.2210/pdb1ute/pdb
• 分子名称: PROTEIN (II PURPLE ACID PHOSPHATASE), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... (6 entities in total)
• 機能のキーワード: purple acid phosphatase, tartrate resistant acid phosphatase, metalloenzyme, uteroferrin, hydrolase
• 由来する生物種: Sus scrofa (pig)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35861.22

構造登録者

Guddat, L.W.,Mcalpine, A.,Hume, D.,Hamilton, S.,De Jersey, J.,Martin, J.L. (登録日: 1999-01-18, 公開日: 1999-10-01, 最終更新日: 2024-11-20)

主引用文献

Guddat, L.W.,McAlpine, A.S.,Hume, D.,Hamilton, S.,de Jersey, J.,Martin, J.L.
Crystal structure of mammalian purple acid phosphatase.
Structure Fold.Des., 7:757-767, 1999

PubMed Abstract: Mammalian purple acid phosphatases are highly conserved binuclear metal-containing enzymes produced by osteoclasts, the cells that resorb bone. The enzyme is a target for drug design because there is strong evidence that it is involved in bone resorption.

PubMed: 10425678
DOI: 10.1016/S0969-2126(99)80100-2

実験手法

X-RAY DIFFRACTION (1.55 Å)