1USB
Rational design of a novel enzyme - efficient thioester hydrolysis enabled by the incorporation of a single His residue into human glutathione transferase A1-1
Summary for 1USB
Entry DOI | 10.2210/pdb1usb/pdb |
Related | 1GSD 1GSE 1GSF 1GUH 1K3L 1K3O 1K3Y 1LBK |
Descriptor | GLUTATHIONE S-TRANSFERASE A1, GLUTATHIONE, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | transferase, glutathione |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 52608.36 |
Authors | Jakobsson, E.,Kleywegt, G.J. (deposition date: 2003-11-20, release date: 2004-09-01, Last modification date: 2023-12-13) |
Primary citation | Hederos, S.,Broo, K.S.,Jakobsson, E.,Kleywegt, G.J.,Mannervik, B.,Baltzer, L. Incorporation of a Single His Residue by Rational Design Enables Thiol-Ester Hydrolysis by Human Glutathione Transferase A1-1 Proc.Natl.Acad.Sci.USA, 101:13163-, 2004 Cited by PubMed: 15333749DOI: 10.1073/PNAS.0403045101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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