1USB

Rational design of a novel enzyme - efficient thioester hydrolysis enabled by the incorporation of a single His residue into human glutathione transferase A1-1

1USB の概要

• エントリーDOI: 10.2210/pdb1usb/pdb
• 関連するPDBエントリー: 1GSD 1GSE 1GSF 1GUH 1K3L 1K3O 1K3Y 1LBK
• 分子名称: GLUTATHIONE S-TRANSFERASE A1, GLUTATHIONE, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: transferase, glutathione
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52608.36

構造登録者

Jakobsson, E.,Kleywegt, G.J. (登録日: 2003-11-20, 公開日: 2004-09-01, 最終更新日: 2023-12-13)

• 主引用文献: Hederos, S.,Broo, K.S.,Jakobsson, E.,Kleywegt, G.J.,Mannervik, B.,Baltzer, L.; Incorporation of a Single His Residue by Rational Design Enables Thiol-Ester Hydrolysis by Human Glutathione Transferase A1-1; Proc.Natl.Acad.Sci.USA, 101:13163-, 2004; PubMed: 15333749; DOI: 10.1073/PNAS.0403045101

実験手法

X-RAY DIFFRACTION (2.07 Å)