1URR

A novel Drosophila Melanogaster Acylphosphatase (AcPDro2)

1URR の概要

• エントリーDOI: 10.2210/pdb1urr/pdb
• 分子名称: CG18505 PROTEIN, GLYCEROL (3 entities in total)
• 機能のキーワード: acylphosphatase, enzyme, hydrolase
• 由来する生物種: DROSOPHILA MELANOGASTER (FRUIT FLY)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11875.63

構造登録者

Rosano, C.,Zuccotti, S.,Bolognesi, M. (登録日: 2003-11-03, 公開日: 2004-05-27, 最終更新日: 2023-12-13)

主引用文献

Zuccotti, S.,Rosano, C.,Ramazzotti, M.,Degl'Innocenti, D.,Stefani, M.,Manao, G.,Bolognesi, M.
Three-Dimensional Structural Characterization of a Novel Drosophila Melanogaster Acylphosphatase
Acta Crystallogr.,Sect.D, 60:1177-, 2004

PubMed Abstract: Analysis of the Drosophila melanogaster EST database led to the discovery and cloning of a novel acylphosphatase. The CG18505 gene coding for a new enzyme (AcPDro2) is clearly distinct from the previously described CG16870Acyp gene, which also codes for a D. melanogaster acylphosphatase (AcPDro). The putative catalytic residues, together with residues held to stabilize the acylphosphatase fold, are conserved in the two encoded proteins. Crystals of AcPDro2, which belong to the trigonal space group P3(1)21, with unit-cell parameters a = b = 45.8, c = 98.6 angstroms, gamma = 120 degrees, allowed the solution of the protein structure by molecular replacement and its refinement to 1.5 angstroms resolution. The AcPDro2 active-site structure is discussed.

PubMed: 15159593
DOI: 10.1107/S0907444904006808

実験手法

X-RAY DIFFRACTION (1.5 Å)