1UK4
Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) Complexed With An Inhibitor
1UK4 の概要
エントリーDOI | 10.2210/pdb1uk4/pdb |
関連するPDBエントリー | 1UK2 1UK3 |
分子名称 | 3C-like proteinase nsp5, 5-mer peptide of inhibitor (3 entities in total) |
機能のキーワード | anti-parallel b-barrel, anti-parallel a-helices, an inhibitor, hydrolase |
由来する生物種 | SARS coronavirus 詳細 |
細胞内の位置 | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P0C6X7 |
タンパク質・核酸の鎖数 | 5 |
化学式量合計 | 69535.45 |
構造登録者 | |
主引用文献 | Yang, H.,Yang, M.,Ding, Y.,Liu, Y.,Lou, Z.,Zhou, Z.,Sun, L.,Mo, L.,Ye, S.,Pang, H.,Gao, G.F.,Anand, K.,Bartlam, M.,Hilgenfeld, R.,Rao, Z. The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor Proc.Natl.Acad.Sci.USA, 100:13190-13195, 2003 Cited by PubMed: 14585926DOI: 10.1073/pnas.1835675100 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.5 Å) |
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