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1UJ1

Crystal structure of SARS Coronavirus Main Proteinase (3CLpro)

Summary for 1UJ1
Entry DOI10.2210/pdb1uj1/pdb
Descriptor3C-like proteinase (2 entities in total)
Functional Keywordsanti-parallel b-barrel, anti-parallel a-helices, hydrolase
Biological sourceSARS coronavirus
Cellular locationNon-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P59641
Total number of polymer chains2
Total formula weight67753.27
Authors
Yang, H.,Yang, M.,Liu, Y.,Bartlam, M.,Ding, Y.,Lou, Z.,Sun, L.,Zhou, Z.,Ye, S.,Anand, K.,Pang, H.,Gao, G.F.,Hilgenfeld, R.,Rao, Z. (deposition date: 2003-07-25, release date: 2003-11-18, Last modification date: 2023-12-27)
Primary citationYang, H.,Yang, M.,Ding, Y.,Liu, Y.,Lou, Z.,Zhou, Z.,Sun, L.,Mo, L.,Ye, S.,Pang, H.,Gao, G.F.,Anand, K.,Bartlam, M.,Hilgenfeld, R.,Rao, Z.
The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100:13190-13195, 2003
Cited by
PubMed: 14585926
DOI: 10.1073/pnas.1835675100
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

217705

数据于2024-03-27公开中

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