1U68 の概要
| 分子名称 | Dihydroneopterin aldolase, 2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE (2 entities in total) |
|---|---|
| 機能のキーワード | 7, dhna, 8 dihydroneopterin, lyase |
| 由来する生物種 | Staphylococcus aureus |
| ポリマー鎖数 | 1 |
| 分子量合計 | 14024.87 |
| 構造登録者 | Sanders, W.J.,Nienaber, V.L.,Lerner, C.G.,McCall, J.O.,Merrick, S.M.,Swanson, S.J.,Harlan, J.E.,Stoll, V.S.,Stamper, G.F.,Betz, S.F.,Condroski, K.R.,Meadows, R.P.,Severin, J.M.,Walter, K.A.,Magdalinos, P.,Jakob, C.G.,Wagner, R.,Beutel, B.A. (登録日: 2004-07-29, 公開日: 2004-10-19, 最終更新日: 2011-07-13) |
| 主引用文献 | Sanders, W.J.,Nienaber, V.L.,Lerner, C.G.,McCall, J.O.,Merrick, S.M.,Swanson, S.J.,Harlan, J.E.,Stoll, V.S.,Stamper, G.F.,Betz, S.F.,Condroski, K.R.,Meadows, R.P.,Severin, J.M.,Walter, K.A.,Magdalinos, P.,Jakob, C.G.,Wagner, R.,Beutel, B.A. Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization. J.MED.CHEM., 47:1709-1718, 2004 PubMed: 15027862 (主引用文献が同じPDBエントリー) DOI: 10.1021/jm030497y  Import into Mendeley |
| 実験手法 | X-RAY DIFFRACTION (2.4 Å) |
| NMR情報 |
