1U5B
Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase
Summary for 1U5B
Entry DOI | 10.2210/pdb1u5b/pdb |
Descriptor | 2-oxoisovalerate dehydrogenase alpha subunit, 2-oxoisovalerate dehydrogenase beta subunit, POTASSIUM ION, ... (7 entities in total) |
Functional Keywords | oxidoreductase, ketoacid dehydrogenase, branched-chain, multi-enzyme complex, acylation, oxidative decarboxylation maple syrup urine disease, thiamin diphosphate, phosphorylation, flavoprotein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 84123.91 |
Authors | Wynn, R.M.,Kato, M.,Machius, M.,Chuang, J.L.,Li, J.,Tomchick, D.R.,Chuang, D.T. (deposition date: 2004-07-27, release date: 2004-11-23, Last modification date: 2023-08-23) |
Primary citation | Wynn, R.M.,Kato, M.,Machius, M.,Chuang, J.L.,Li, J.,Tomchick, D.R.,Chuang, D.T. Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation Structure, 12:2185-2196, 2004 Cited by PubMed: 15576032DOI: 10.1016/j.str.2004.09.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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