1TUG

Aspartate Transcarbamoylase Catalytic Chain Mutant E50A Complex with Phosphonoacetamide, Malonate, and Cytidine-5-Prime-Triphosphate (CTP)

1TUG の概要

• エントリーDOI: 10.2210/pdb1tug/pdb
• 関連するPDBエントリー: 1NBE 1TTH 1TU0 3AT1
• 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, MALONATE ION, ... (7 entities in total)
• 機能のキーワード: protein structure-function, site specific mutagenesis, domain closure, allosteric transition, hydrolase-hydrolase regulator complex, hydrolase/hydrolase regulator
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 104424.71

構造登録者

Stieglitz, K.,Stec, B.,Baker, D.P.,Kantrowitz, E.R. (登録日: 2004-06-24, 公開日: 2004-07-20, 最終更新日: 2024-04-03)

• 主引用文献: Stieglitz, K.,Stec, B.,Baker, D.P.,Kantrowitz, E.R.; Monitoring the Transition from the T to the R State in E.coli Aspartate Transcarbamoylase by X-ray Crystallography: Crystal Structures of the E50A Mutant Enzyme in Four Distinct Allosteric States.; J.Mol.Biol., 341:853-868, 2004; PubMed: 15288791; DOI: 10.1016/j.jmb.2004.06.002

実験手法

X-RAY DIFFRACTION (2.1 Å)