1TRV

THE HIGH-RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURES OF THE OXIDIZED AND REDUCED STATES OF HUMAN THIOREDOXIN

1TRV の概要

• エントリーDOI: 10.2210/pdb1trv/pdb
• 分子名称: THIOREDOXIN (2 entities in total)
• 機能のキーワード: electron transport
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: P10599
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11624.19

構造登録者

Clore, G.M.,Qin, J.,Gronenborn, A.M. (登録日: 1994-05-10, 公開日: 1994-09-30, 最終更新日: 2024-05-22)

主引用文献

Qin, J.,Clore, G.M.,Gronenborn, A.M.
The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure, 2:503-522, 1994

PubMed Abstract: Thioredoxin is a ubiquitous protein and is involved in a variety of fundamental biological functions. Its active site is conserved and has two redox active cysteines in the sequence Trp-Cys-Gly-Pro-Cys. No structures of the oxidized and reduced states from the same species have been determined at high resolution under the same conditions and using the same methods. Hence, any detailed comparison of the two oxidation states has been previously precluded.

PubMed: 7922028
DOI: 10.1016/S0969-2126(00)00051-4

実験手法

SOLUTION NMR