1TPU

S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE

1TPU の概要

• エントリーDOI: 10.2210/pdb1tpu/pdb
• 分子名称: TRIOSEPHOSPHATE ISOMERASE, PHOSPHOGLYCOLOHYDROXAMIC ACID (3 entities in total)
• 機能のキーワード: isomerase(intramolecular oxidoreductase)
• 由来する生物種: Gallus gallus (chicken)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53374.58

構造登録者

Zhang, Z.,Sugio, S.,Komives, E.A.,Liu, K.D.,Stock, A.M.,Narayana, N.,Xuong, Ng.H.,Knowles, J.R.,Petsko, G.A.,Ringe, D. (登録日: 1994-11-07, 公開日: 1995-04-20, 最終更新日: 2024-02-14)

• 主引用文献: Komives, E.A.,Lougheed, J.C.,Zhang, Z.,Sugio, S.,Narayana, N.,Xuong, N.H.,Petsko, G.A.,Ringe, D.; The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.; Biochemistry, 35:15474-15484, 1996; PubMed: 8952501; DOI: 10.1021/bi961556v

実験手法

X-RAY DIFFRACTION (1.9 Å)