1TNN

Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new member of the I set

1TNN の概要

• エントリーDOI: 10.2210/pdb1tnn/pdb
• 分子名称: TITIN MODULE M5 (1 entity in total)
• 機能のキーワード: muscle protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm : Q8WZ42
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11295.47

構造登録者

Pfuhl, M.,Pastore, A. (登録日: 1995-01-17, 公開日: 1995-04-20, 最終更新日: 2024-05-01)

主引用文献

Pfuhl, M.,Pastore, A.
Tertiary structure of an immunoglobulin-like domain from the giant muscle protein titin: a new member of the I set.
Structure, 3:391-401, 1995

PubMed Abstract: Titin is a gigantic protein located in the thick filament of vertebrate muscles. The putative functions of titin range from interactions with myosin and other muscle proteins to a role in muscle recoil. Analysis of its complete sequence has shown that titin is a multi-domain protein containing several copies of modules of 100 amino acids each. These are thought to belong to the fibronectin type-III and immunoglobulin superfamilies. So far, a complete structural determination has not been carried out on any of the titin modules.

PubMed: 7613868
DOI: 10.1016/S0969-2126(01)00170-8

実験手法

SOLUTION NMR