1TLP

CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN

1TLP の概要

• エントリーDOI: 10.2210/pdb1tlp/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000638
• 分子名称: THERMOLYSIN, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: metalloproteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Bacillus thermoproteolyticus
• 細胞内の位置: Secreted: P00800
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35131.53

構造登録者

Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W. (登録日: 1987-06-29, 公開日: 1989-01-09, 最終更新日: 2024-03-13)

• 主引用文献: Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W.; Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin.; Eur.J.Biochem., 157:261-268, 1986; PubMed: 3709536; DOI: 10.1111/j.1432-1033.1986.tb09664.x

実験手法

X-RAY DIFFRACTION (2.3 Å)