1TLP

CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN

1TLP の概要

関連するBIRD辞書のPRD_IDPRD_000638
分子名称THERMOLYSIN, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, CALCIUM ION, ... (5 entities in total)
機能のキーワードmetalloproteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
由来する生物種Bacillus thermoproteolyticus
詳細
細胞内の位置Secreted P00800
ポリマー鎖数1
分子量合計35131.53
構造登録者
Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W. (登録日: 1987-06-29, 公開日: 1989-01-09, 最終更新日: 2017-11-29)
主引用文献
Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W.
Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin.
Eur.J.Biochem., 157:261-268, 1986
PubMed: 3709536 (主引用文献が同じPDBエントリー)
DOI: 10.1111/j.1432-1033.1986.tb09664.x
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.3 Å)
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers708.7%0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード

他の静止画像(非対称単位)

Molmil generated image of 1tlp
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Molmil generated image of 1tlp
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Molmil generated image of 1tlp
y軸(上下方向)周りに90°回転