1THL
Thermolysin complexed with a novel glutaramide derivative, n-(1-(2(r,s)-carboxy-4-phenylbutyl) cyclopentylcarbonyl)-(s)-tryptophan
Summary for 1THL
Entry DOI | 10.2210/pdb1thl/pdb |
Related PRD ID | PRD_000237 |
Descriptor | THERMOLYSIN, CALCIUM ION, ZINC ION, ... (5 entities in total) |
Functional Keywords | metalloproteinase, glutaramide derivative, thermolysin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bacillus thermoproteolyticus |
Cellular location | Secreted: P00800 |
Total number of polymer chains | 1 |
Total formula weight | 35064.59 |
Authors | Holland, D.R.,Matthews, B.W. (deposition date: 1993-11-17, release date: 1994-01-31, Last modification date: 2024-05-22) |
Primary citation | Holland, D.R.,Barclay, P.L.,Danilewicz, J.C.,Matthews, B.W.,James, K. Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex Biochemistry, 33:51-56, 1994 Cited by PubMed: 8286362DOI: 10.1021/bi00167a007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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