1THL

Thermolysin complexed with a novel glutaramide derivative, n-(1-(2(r,s)-carboxy-4-phenylbutyl) cyclopentylcarbonyl)-(s)-tryptophan

1THL の概要

関連するBIRD辞書のPRD_IDPRD_000237
分子名称THERMOLYSIN, CALCIUM ION, ZINC ION, ... (5 entities in total)
機能のキーワードmetalloproteinase, glutaramide derivative, thermolysin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
由来する生物種Bacillus thermoproteolyticus
細胞内の位置Secreted P00800
ポリマー鎖数1
分子量合計35064.59
構造登録者
Holland, D.R.,Matthews, B.W. (登録日: 1993-11-17, 公開日: 1994-01-31, 最終更新日: 2012-12-12)
主引用文献
Holland, D.R.,Barclay, P.L.,Danilewicz, J.C.,Matthews, B.W.,James, K.
Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex
Biochemistry, 33:51-56, 1994
PubMed: 8286362 (主引用文献が同じPDBエントリー)
DOI: 10.1021/bi00167a007
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.7 Å)
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers906.0%0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード

他の静止画像(非対称単位)

Molmil generated image of 1thl
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Molmil generated image of 1thl
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Molmil generated image of 1thl
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