1TG4

Design of specific inhibitors of groupII phospholipase A2(PLA2): Crystal structure of the complex formed between russells viper PLA2 and designed peptide Phe-Leu-Ala-Tyr-Lys at 1.7A resolution

Summary for 1TG4

• Entry DOI: 10.2210/pdb1tg4/pdb
• Related: 1SKG 1TGM 1TH6 1TI0 1TJ9
• Descriptor: Phospholipase A2, FLAYK peptide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: phospholipase a2, flayk, complex, specific inhibitor, hydrolase
• Biological source: Daboia russellii russellii
• Cellular location: Secreted: P59071
• Total number of polymer chains: 2
• Total formula weight: 14751.86

Authors

Singh, N.,Somvanshi, R.K.,Sharma, S.,Dey, S.,Perbandt, M.,Betzel, C.,Ethayathulla, A.S.,Singh, T.P. (deposition date: 2004-05-28, release date: 2004-06-08, Last modification date: 2023-08-23)

• Primary citation: Singh, N.,Somvanshi, R.K.,Sharma, S.,Dey, S.,Perbandt, M.,Betzel, C.,Ethayathulla, A.S.,Singh, T.P.; Design of specific inhibitors of groupII phospholipase A2(PLA2): Crystal structure of the complex formed between russells viper PLA2 and designed peptide Phe-Leu-Ala-Tyr-Lys at 1.7A resolution; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (1.7 Å)