1TFX
COMPLEX OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR WITH PORCINE TRYPSIN
Summary for 1TFX
Entry DOI | 10.2210/pdb1tfx/pdb |
Descriptor | TRYPSIN, TISSUE FACTOR PATHWAY INHIBITOR, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | complex (serine protease-inhibitor), hydrolase, inhibitor, blood coagulation, complex (serine protease-inhibitor) complex, complex (serine protease/inhibitor) |
Biological source | Sus scrofa (pig) More |
Cellular location | Secreted, extracellular space: P00761 Secreted: P10646 |
Total number of polymer chains | 4 |
Total formula weight | 60774.48 |
Authors | Stubbs, M.T.,Huber, R. (deposition date: 1997-01-21, release date: 1998-01-21, Last modification date: 2023-08-09) |
Primary citation | Burgering, M.J.,Orbons, L.P.,van der Doelen, A.,Mulders, J.,Theunissen, H.J.,Grootenhuis, P.D.,Bode, W.,Huber, R.,Stubbs, M.T. The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa. J.Mol.Biol., 269:395-407, 1997 Cited by PubMed: 9199408DOI: 10.1006/jmbi.1997.1029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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