1TFH

EXTRACELLULAR DOMAIN OF HUMAN TISSUE FACTOR

Summary for 1TFH

• Entry DOI: 10.2210/pdb1tfh/pdb
• Descriptor: HUMAN TISSUE FACTOR (2 entities in total)
• Functional Keywords: blood coagulation, tissue factor, coagulation factor, glycoprotein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 49653.02

Authors

Huang, M.,Syed, R.,Stura, E.A.,Stone, M.J.,Stefanko, R.S.,Ruf, W.,Edgington, T.S.,Wilson, I.A. (deposition date: 1997-04-10, release date: 1998-02-25, Last modification date: 2023-08-09)

• Primary citation: Huang, M.,Syed, R.,Stura, E.A.,Stone, M.J.,Stefanko, R.S.,Ruf, W.,Edgington, T.S.,Wilson, I.A.; The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex.; J.Mol.Biol., 275:873-894, 1998; PubMed: 9480775; DOI: 10.1006/jmbi.1997.1512

Experimental method

X-RAY DIFFRACTION (2.4 Å)