1TFH
EXTRACELLULAR DOMAIN OF HUMAN TISSUE FACTOR
Summary for 1TFH
Entry DOI | 10.2210/pdb1tfh/pdb |
Descriptor | HUMAN TISSUE FACTOR (2 entities in total) |
Functional Keywords | blood coagulation, tissue factor, coagulation factor, glycoprotein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 49653.02 |
Authors | Huang, M.,Syed, R.,Stura, E.A.,Stone, M.J.,Stefanko, R.S.,Ruf, W.,Edgington, T.S.,Wilson, I.A. (deposition date: 1997-04-10, release date: 1998-02-25, Last modification date: 2023-08-09) |
Primary citation | Huang, M.,Syed, R.,Stura, E.A.,Stone, M.J.,Stefanko, R.S.,Ruf, W.,Edgington, T.S.,Wilson, I.A. The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex. J.Mol.Biol., 275:873-894, 1998 Cited by PubMed: 9480775DOI: 10.1006/jmbi.1997.1512 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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