1TFH

EXTRACELLULAR DOMAIN OF HUMAN TISSUE FACTOR

1TFH の概要

• エントリーDOI: 10.2210/pdb1tfh/pdb
• 分子名称: HUMAN TISSUE FACTOR (2 entities in total)
• 機能のキーワード: blood coagulation, tissue factor, coagulation factor, glycoprotein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49653.02

構造登録者

Huang, M.,Syed, R.,Stura, E.A.,Stone, M.J.,Stefanko, R.S.,Ruf, W.,Edgington, T.S.,Wilson, I.A. (登録日: 1997-04-10, 公開日: 1998-02-25, 最終更新日: 2023-08-09)

• 主引用文献: Huang, M.,Syed, R.,Stura, E.A.,Stone, M.J.,Stefanko, R.S.,Ruf, W.,Edgington, T.S.,Wilson, I.A.; The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex.; J.Mol.Biol., 275:873-894, 1998; PubMed: 9480775; DOI: 10.1006/jmbi.1997.1512

実験手法

X-RAY DIFFRACTION (2.4 Å)