1TEM

6 ALPHA HYDROXYMETHYL PENICILLOIC ACID ACYLATED ON THE TEM-1 BETA-LACTAMASE FROM ESCHERICHIA COLI

1TEM の概要

• エントリーDOI: 10.2210/pdb1tem/pdb
• 分子名称: TEM-1 BETA LACTAMASE, 2-(1-CARBOXY-2-HYDROXY-ETHYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID (3 entities in total)
• 機能のキーワード: hydrolase, antibiotic resistance, transposable element
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29233.36

構造登録者

Maveyraud, L.,Massova, I.,Samama, J.P.,Mobashery, S. (登録日: 1996-05-28, 公開日: 1997-05-15, 最終更新日: 2011-07-13)

• 主引用文献: Maveyraud, L.,Massova, I.,Birck, C.,Miyashita, K.,Samama, J.P.,Mobashery, S.; Crystal Structure of 6Alpha-Hydroxymethylpenicillanate Complexed to the Tem-1 Beta-Lactamase from Escherichia Coli: Evidence on the Mechanism of Action of a Novel Inhibitor Designed by a Computer-Aided Process; J.Am.Chem.Soc., 118:7435-, 1996

実験手法

X-RAY DIFFRACTION (1.95 Å)