1TB6

2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex

1TB6 の概要

• エントリーDOI: 10.2210/pdb1tb6/pdb
• 分子名称: thrombin, Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: heparin, hydrolase-blood clotting complex, hydrolase/blood clotting
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 92162.06

構造登録者

Li, W.,Johnson, D.J.,Esmon, C.T.,Huntington, J.A. (登録日: 2004-05-19, 公開日: 2004-08-17, 最終更新日: 2023-08-23)

• 主引用文献: Li, W.,Johnson, D.J.,Esmon, C.T.,Huntington, J.A.; Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.; Nat.Struct.Mol.Biol., 11:857-862, 2004; PubMed: 15311269; DOI: 10.1038/nsmb811

実験手法

X-RAY DIFFRACTION (2.5 Å)