1T9W
Structural Basis of Multidrug Transport by the AcrB Multidrug Efflux Pump
Summary for 1T9W
| Entry DOI | 10.2210/pdb1t9w/pdb |
| Descriptor | Acriflavine resistance protein B, 6-[[(2-ETHOXY-1-NAPHTHALENYL)CARBONYL]AMINO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE (2 entities in total) |
| Functional Keywords | membrane protein, 12 transmembranes |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 114449.08 |
| Authors | Yu, E.W.,McDermott, G.,Nikaido, H. (deposition date: 2004-05-18, release date: 2005-10-04, Last modification date: 2024-02-14) |
| Primary citation | Yu, E.W.,Aires, J.R.,McDermott, G.,Nikaido, H. A Periplasmic Drug-Binding Site of the AcrB Multidrug Efflux Pump: a Crystallographic and Site-Directed Mutagenesis Study J.Bacteriol., 187:6804-6815, 2005 Cited by PubMed: 16166543DOI: 10.1128/JB.187.19.6804-6815.2005 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.23 Å) |
Structure validation
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