Crystal structure of mutant Lys8Asp of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch

Summary for 1T7A

Related1sn1 1t7b 1t7e
DescriptorAlpha-like neurotoxin BmK-I (2 entities in total)
Functional Keywordsintramolecular switch, cis/trans isomerization, non-proline peptide bond, scorpion toxin, toxin
Biological sourceMesobuthus martensii (Chinese scorpion)
Cellular locationSecreted P45697
Total number of polymer chains1
Total molecular weight7422.36
Xiang, Y.,Guan, R.J.,He, X.L.,Wang, C.G.,Wang, M.,Zhang, Y.,Sundberg, E.J.,Wang, D.C. (deposition date: 2004-05-08, release date: 2004-09-07, Last modification date: 2011-07-13)
Primary citation
Guan, R.J.,Xiang, Y.,He, X.L.,Wang, C.G.,Wang, M.,Zhang, Y.,Sundberg, E.J.,Wang, D.C.
Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
J.Mol.Biol., 341:1189-1204, 2004
PubMed: 15321715 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2004.06.067
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.184605.4%4.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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