1SQI

Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases

Summary for 1SQI

• Entry DOI: 10.2210/pdb1sqi/pdb
• Related: 1SQD
• Descriptor: 4-hydroxyphenylpyruvic acid dioxygenase, FE (III) ION, (1-TERT-BUTYL-5-HYDROXY-1H-PYRAZOL-4-YL)[6-(METHYLSULFONYL)-4'-METHOXY-2-METHYL-1,1'-BIPHENYL-3-YL]METHANONE, ... (4 entities in total)
• Functional Keywords: rat 4-hydroxyphenylpyruvate dioxygenase, biosynthetic protein
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Cytoplasm: P32755
• Total number of polymer chains: 2
• Total formula weight: 91458.90

Authors

Yang, C.,Pflugrath, J.W.,Camper, D.L.,Foster, M.L.,Pernich, D.J.,Walsh, T.A. (deposition date: 2004-03-18, release date: 2004-08-17, Last modification date: 2024-02-14)

• Primary citation: Yang, C.,Pflugrath, J.W.,Camper, D.L.,Foster, M.L.,Pernich, D.J.,Walsh, T.A.; Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases; Biochemistry, 43:10414-10423, 2004; PubMed: 15301540; DOI: 10.1021/bi049323o

Experimental method

X-RAY DIFFRACTION (2.15 Å)