1SQI

Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases

1SQI の概要

• エントリーDOI: 10.2210/pdb1sqi/pdb
• 関連するPDBエントリー: 1SQD
• 分子名称: 4-hydroxyphenylpyruvic acid dioxygenase, FE (III) ION, (1-TERT-BUTYL-5-HYDROXY-1H-PYRAZOL-4-YL)[6-(METHYLSULFONYL)-4'-METHOXY-2-METHYL-1,1'-BIPHENYL-3-YL]METHANONE, ... (4 entities in total)
• 機能のキーワード: rat 4-hydroxyphenylpyruvate dioxygenase, biosynthetic protein
• 由来する生物種: Rattus norvegicus (Norway rat)
• 細胞内の位置: Cytoplasm: P32755
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 91458.90

構造登録者

Yang, C.,Pflugrath, J.W.,Camper, D.L.,Foster, M.L.,Pernich, D.J.,Walsh, T.A. (登録日: 2004-03-18, 公開日: 2004-08-17, 最終更新日: 2024-02-14)

• 主引用文献: Yang, C.,Pflugrath, J.W.,Camper, D.L.,Foster, M.L.,Pernich, D.J.,Walsh, T.A.; Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases; Biochemistry, 43:10414-10423, 2004; PubMed: 15301540; DOI: 10.1021/bi049323o

実験手法

X-RAY DIFFRACTION (2.15 Å)