1SQ5

Crystal Structure of E. coli Pantothenate kinase

Summary for 1SQ5

• Entry DOI: 10.2210/pdb1sq5/pdb
• Related: 1ESM 1ESN
• Descriptor: Pantothenate kinase, PANTOTHENOIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: p-loop, transferase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm (Probable): P0A6I3
• Total number of polymer chains: 4
• Total formula weight: 144480.14

Authors

Ivey, R.A.,Zhang, Y.-M.,Virga, K.G.,Hevener, K.,Lee, R.E.,Rock, C.O.,Jackowski, S.,Park, H.-W. (deposition date: 2004-03-17, release date: 2004-09-28, Last modification date: 2024-02-14)

• Primary citation: Ivey, R.A.,Zhang, Y.-M.,Virga, K.G.,Hevener, K.,Lee, R.E.,Rock, C.O.,Jackowski, S.,Park, H.-W.; The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites.; J.Biol.Chem., 279:35622-35629, 2004; PubMed: 15136582; DOI: 10.1074/jbc.M403152200

Experimental method

X-RAY DIFFRACTION (2.2 Å)