1SPA

ROLE OF ASP222 IN THE CATALYTIC MECHANISM OF ESCHERICHIA COLI ASPARTATE AMINOTRANSFERASE: THE AMINO ACID RESIDUE WHICH ENHANCES THE FUNCTION OF THE ENZYME-BOUND COENZYME PYRIDOXAL 5'-PHOSPHATE

1SPA の概要

• エントリーDOI: 10.2210/pdb1spa/pdb
• 分子名称: ASPARTATE AMINOTRANSFERASE, N-METHYL-4-DEOXY-4-AMINO-PYRIDOXAL-5-PHOSPHATE (3 entities in total)
• 機能のキーワード: transferase(aminotransferase)
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm: P00509
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43838.41

構造登録者

Hinoue, Y.,Yano, T.,Metzler, D.E.,Miyahara, I.,Hirotsu, K.,Kagamiyama, H. (登録日: 1993-01-26, 公開日: 1993-10-31, 最終更新日: 2024-02-14)

• 主引用文献: Yano, T.,Kuramitsu, S.,Tanase, S.,Morino, Y.,Kagamiyama, H.; Role of Asp222 in the catalytic mechanism of Escherichia coli aspartate aminotransferase: the amino acid residue which enhances the function of the enzyme-bound coenzyme pyridoxal 5'-phosphate.; Biochemistry, 31:5878-5887, 1992; PubMed: 1610831; DOI: 10.1021/bi00140a025

実験手法

X-RAY DIFFRACTION (2 Å)