1SP3

Crystal structure of octaheme cytochrome c from Shewanella oneidensis

1SP3 の概要

• エントリーDOI: 10.2210/pdb1sp3/pdb
• 分子名称: cytochrome c, putative, THIOCYANATE ION, HEME C, ... (4 entities in total)
• 機能のキーワード: octaheme, cytochrome c, oxidoreductase
• 由来する生物種: Shewanella oneidensis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54577.70

構造登録者

Mowat, C.G.,Rothery, E.,Miles, C.S.,McIver, L.,Doherty, M.K.,Drewette, K.,Taylor, P.,Walkinshaw, M.D.,Chapman, S.K.,Reid, G.A. (登録日: 2004-03-16, 公開日: 2004-09-21, 最終更新日: 2021-03-03)

主引用文献

Mowat, C.G.,Rothery, E.,Miles, C.S.,McIver, L.,Doherty, M.K.,Drewette, K.,Taylor, P.,Walkinshaw, M.D.,Chapman, S.K.,Reid, G.A.
Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation.
Nat.Struct.Mol.Biol., 11:1023-1024, 2004

PubMed Abstract: We have isolated a soluble cytochrome from Shewanella oneidensis that contains eight covalently attached heme groups and determined its crystal structure. One of these hemes exhibits novel ligation of the iron atom by the epsilon-amino group of a lysine residue, despite its attachment via a typical CXXCH motif. This heme is most likely the active site for tetrathionate reduction, a reaction catalyzed efficiently by this enzyme.

PubMed: 15361860
DOI: 10.1038/nsmb827

実験手法

X-RAY DIFFRACTION (2.2 Å)