1SNG

Structure of a Thermophilic Serpin in the Native State

Summary for 1SNG

• Entry DOI: 10.2210/pdb1sng/pdb
• Related: 1mtp
• Descriptor: COG4826: Serine protease inhibitor, SULFATE ION (3 entities in total)
• Functional Keywords: serine protease inhibitor (serpin), native state., hydrolase inhibitor
• Biological source: Thermobifida fusca
• Total number of polymer chains: 1
• Total formula weight: 40619.07

Authors

Fulton, K.F.,Buckle, A.M.,Cabrita, L.D.,Irving, J.A.,Butcher, R.E.,Smith, I.,Reeve, S.,Lesk, A.M.,Bottomley, S.P.,Rossjohn, J.,Whisstock, J.C. (deposition date: 2004-03-10, release date: 2004-12-14, Last modification date: 2023-08-23)

• Primary citation: Fulton, K.F.,Buckle, A.M.,Cabrita, L.D.,Irving, J.A.,Butcher, R.E.,Smith, I.,Reeve, S.,Lesk, A.M.,Bottomley, S.P.,Rossjohn, J.,Whisstock, J.C.; The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition.; J.Biol.Chem., 280:8435-8442, 2005; PubMed: 15590653; DOI: 10.1074/jbc.M410206200

Experimental method

X-RAY DIFFRACTION (1.76 Å)