1SLX
RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; ZINC-BOUND
Summary for 1SLX
Entry DOI | 10.2210/pdb1slx/pdb |
Descriptor | ECOTIN, ANIONIC TRYPSIN, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | serine protease, inhibitor, complex, metal binding sites, protein engineering, protease-substrate interactions, metalloproteins, complex (serine protease-inhibitor) complex, complex (serine protease/inhibitor) |
Biological source | Escherichia coli More |
Cellular location | Periplasm: P23827 Secreted, extracellular space: P00763 |
Total number of polymer chains | 2 |
Total formula weight | 40200.02 |
Authors | Brinen, L.S.,Fletterick, R.J. (deposition date: 1996-02-07, release date: 1996-07-11, Last modification date: 2021-11-03) |
Primary citation | Brinen, L.S.,Willett, W.S.,Craik, C.S.,Fletterick, R.J. X-ray structures of a designed binding site in trypsin show metal-dependent geometry. Biochemistry, 35:5999-6009, 1996 Cited by PubMed: 8634241DOI: 10.1021/bi9530200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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