1SL6

Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.

Summary for 1SL6

Entry DOI	10.2210/pdb1sl6/pdb
Related PRD ID	PRD_900120
Descriptor	C-type lectin DC-SIGNR, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, ... (4 entities in total)
Functional Keywords	dc-signr, c-type lectin, sugar binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	6
Total formula weight	132565.85
Authors	Guo, Y.,Feinberg, H.,Conroy, E.,Mitchell, D.A.,Alvarez, R.,Blixt, O.,Taylor, M.E.,Weis, W.I.,Drickamer, K. (deposition date: 2004-03-05, release date: 2004-06-15, Last modification date: 2020-07-29)
Primary citation	Guo, Y.,Feinberg, H.,Conroy, E.,Mitchell, D.A.,Alvarez, R.,Blixt, O.,Taylor, M.E.,Weis, W.I.,Drickamer, K. Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR Nat.Struct.Mol.Biol., 11:591-598, 2004 Cited by PubMed: 15195147 DOI: 10.1038/nsmb784 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation