1SL6

Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.

Summary for 1SL6

DescriptorC-type lectin DC-SIGNR, BETA-D-GALACTOSE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ... (6 entities in total)
Functional Keywordsdc-signr, c-type lectin, sugar binding protein
Biological sourceHomo sapiens (human)
Total number of polymer chains6
Total molecular weight132782.03
Authors
Guo, Y.,Feinberg, H.,Conroy, E.,Mitchell, D.A.,Alvarez, R.,Blixt, O.,Taylor, M.E.,Weis, W.I.,Drickamer, K. (deposition date: 2004-03-05, release date: 2004-06-15, Last modification date: 2011-07-13)
Primary citation
Guo, Y.,Feinberg, H.,Conroy, E.,Mitchell, D.A.,Alvarez, R.,Blixt, O.,Taylor, M.E.,Weis, W.I.,Drickamer, K.
Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11:591-598, 2004
PubMed: 15195147 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb784
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.25 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.262100.7%3.3%4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution