1SJW

Structure of polyketide cyclase SnoaL

1SJW の概要

• エントリーDOI: 10.2210/pdb1sjw/pdb
• 分子名称: nogalonic acid methyl ester cyclase, METHYL 5,7-DIHYDROXY-2-METHYL-4,6,11-TRIOXO-3,4,6,11-TETRAHYDROTETRACENE-1-CARBOXYLATE (3 entities in total)
• 機能のキーワード: anthracyclines, nogalamycin, snoal, aldol condensation, lyase, structural genomics, structural proteomics in europe, spine
• 由来する生物種: Streptomyces nogalater
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17167.22

構造登録者

Sultana, A.,Kallio, P.,Jansson, A.,Wang, J.S.,Neimi, J.,Mantsala, P.,Schneider, G.,Structural Proteomics in Europe (SPINE) (登録日: 2004-03-04, 公開日: 2004-04-27, 最終更新日: 2024-04-03)

• 主引用文献: Sultana, A.,Kallio, P.,Jansson, A.,Wang, J.S.,Niemi, J.,Schneider, G.; Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation.; Embo J., 23:1911-1921, 2004; PubMed: 15071504; DOI: 10.1038/sj.emboj.7600201

実験手法

X-RAY DIFFRACTION (1.35 Å)