1SJE

HLA-DR1 complexed with a 16 residue HIV capsid peptide bound in a hairpin conformation

1SJE の概要

• エントリーDOI: 10.2210/pdb1sje/pdb
• 関連するPDBエントリー: 1KLU 1PYW 1SJH
• 分子名称: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, GAG polyprotein, ... (5 entities in total)
• 機能のキーワード: mhc class ii, major histocompatibility protein complex, hla-dr1, hiv-1, capsid, superantigen, antigen, gag, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein: P01903 P04229; Gag polyprotein: Host cell membrane ; Lipid-anchor . Matrix protein p17: Virion membrane ; Lipid-anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : P12495; Secreted: P0A0L5
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 72361.17

構造登録者

Zavala-Ruiz, Z.,Strug, I.,Walker, B.D.,Norris, P.J.,Stern, L.J. (登録日: 2004-03-03, 公開日: 2004-08-17, 最終更新日: 2023-08-23)

• 主引用文献: Zavala-Ruiz, Z.,Strug, I.,Walker, B.D.,Norris, P.J.,Stern, L.J.; A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.; Proc.Natl.Acad.Sci.Usa, 101:13279-13284, 2004; PubMed: 15331779; DOI: 10.1073/pnas.0403371101

実験手法

X-RAY DIFFRACTION (2.45 Å)