1SI4
Crystal structure of Human hemoglobin A2 (in R2 state) at 2.2 A resolution
Summary for 1SI4
Entry DOI | 10.2210/pdb1si4/pdb |
Related | 1SHR |
Descriptor | Hemoglobin alpha chain, Hemoglobin delta chain, CYANIDE ION, ... (5 entities in total) |
Functional Keywords | hemoglobin a2, beta thalassemia, oxygen transport, antisickling effect, oxygen storage-transport complex, oxygen storage/transport |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 64763.26 |
Authors | Sen, U.,Dasgupta, J.,Choudhury, D.,Datta, P.,Chakrabarti, A.,Chakrabarty, S.B.,Chakrabarty, A.,Dattagupta, J.K. (deposition date: 2004-02-27, release date: 2004-10-26, Last modification date: 2023-10-25) |
Primary citation | Sen, U.,Dasgupta, J.,Choudhury, D.,Datta, P.,Chakrabarti, A.,Chakrabarty, S.B.,Chakrabarty, A.,Dattagupta, J.K. Crystal structures of HbA2 and HbE and modeling of hemoglobin delta4: interpretation of the thermal stability and the antisickling effect of HbA2 and identification of the ferrocyanide binding site in Hb. Biochemistry, 43:12477-12488, 2004 Cited by PubMed: 15449937DOI: 10.1021/bi048903i PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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