1SGY

TYR 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5

Summary for 1SGY

• Entry DOI: 10.2210/pdb1sgy/pdb
• Descriptor: Streptogrisin B, Ovomucoid, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: complex (serine protease-inhibitor), serine proteinase, protein inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Meleagris gallopavo (turkey); More
• Cellular location: Secreted: P68390
• Total number of polymer chains: 2
• Total formula weight: 24383.51

Authors

Huang, K.,Lu, W.,Anderson, S.,Laskowski Jr., M.,James, M.N.G. (deposition date: 1999-03-25, release date: 2003-08-26, Last modification date: 2023-08-23)

• Primary citation: Huang, K.,Lu, W.,Anderson, S.,Laskowski Jr., M.,James, M.N.G.; Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)