1SGY

TYR 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5

1SGY の概要

• エントリーDOI: 10.2210/pdb1sgy/pdb
• 分子名称: Streptogrisin B, Ovomucoid, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: complex (serine protease-inhibitor), serine proteinase, protein inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Meleagris gallopavo (turkey); 詳細
• 細胞内の位置: Secreted: P68390
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 24383.51

構造登録者

Huang, K.,Lu, W.,Anderson, S.,Laskowski Jr., M.,James, M.N.G. (登録日: 1999-03-25, 公開日: 2003-08-26, 最終更新日: 2023-08-23)

• 主引用文献: Huang, K.,Lu, W.,Anderson, S.,Laskowski Jr., M.,James, M.N.G.; Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's; To be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)