1SFP

CRYSTAL STRUCTURE OF ACIDIC SEMINAL FLUID PROTEIN (ASFP) AT 1.9 A RESOLUTION: A BOVINE POLYPEPTIDE FROM THE SPERMADHESIN FAMILY

Summary for 1SFP

• Entry DOI: 10.2210/pdb1sfp/pdb
• Descriptor: ASFP (2 entities in total)
• Functional Keywords: spermadhesin, bovine seminal plasma protein, acidic seminal fluid protein, asfp, cub domain, x-ray crystal structure, growth factor
• Biological source: Bos taurus (cattle)
• Cellular location: Secreted: P29392
• Total number of polymer chains: 1
• Total formula weight: 12932.74

Authors

Romao, M.J.,Kolln, I.,Dias, J.M.,Carvalho, A.L.,Romero, A.,Varela, P.F.,Sanz, L.,Topfer-Petersen, E.,Calvete, J.J. (deposition date: 1997-06-24, release date: 1998-06-24, Last modification date: 2024-10-30)

Primary citation

Romero, A.,Romao, M.J.,Varela, P.F.,Kolln, I.,Dias, J.M.,Carvalho, A.L.,Sanz, L.,Topfer-Petersen, E.,Calvete, J.J.
The crystal structures of two spermadhesins reveal the CUB domain fold.
Nat.Struct.Biol., 4:783-788, 1997

PubMed Abstract: Spermadhesins, 12,000-14,000 M(r) mammalian proteins, include lectins involved in sperm-egg binding and display a single CUB domain architecture. We report the crystal structures of porcine seminal plasma PSP-I/PSP-II, a heterodimer of two glycosylated spermadhesins, and bovine aSFP at 2.4 A and 1.9 A resolution respectively.

PubMed: 9334740
DOI: 10.1038/nsb1097-783

Experimental method

X-RAY DIFFRACTION (1.9 Å)