1SEB

COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 AND THE BACTERIAL SUPERANTIGEN SEB

Summary for 1SEB

DescriptorHLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ENDOGENOUS PEPTIDE MODEL, POLY-ALA, ENTEROTOXIN TYPE B, ... (4 entities in total)
Functional Keywordshistocompatibility antigen, mhc ii, superantigen, enterotoxin peptide, toxin, complex (mhc ii-peptide-toxin) complex, complex (mhc ii/peptide/toxin)
Biological sourceHomo sapiens (human)
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Cellular locationCell membrane; Single-pass type I membrane protein P01903 P04229
Secreted P01552
Total number of polymer chains8
Total molecular weight144654.9
Authors
Jardetzky, T.S.,Brown, J.H.,Gorga, J.C.,Stern, L.J.,Urban, R.G.,Chi, Y.I.,Stauffacher, C.,Strominger, J.L.,Wiley, D.C. (deposition date: 1995-11-26, release date: 1996-06-20, Last modification date: 2011-07-13)
Primary citation
Jardetzky, T.S.,Brown, J.H.,Gorga, J.C.,Stern, L.J.,Urban, R.G.,Chi, Y.I.,Stauffacher, C.,Strominger, J.L.,Wiley, D.C.
Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen.
Nature, 368:711-718, 1994
PubMed: 8152483 (PDB entries with the same primary citation)
DOI: 10.1038/368711a0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers213.2%7.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report